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Harnessing epithelial-mesenchymal plasticity to boost cancer immunotherapy

Immune checkpoint blockade (ICB) therapy is a powerful option for cancer treatment. Despite demonstrable progress, most patients fail to respond or achieve durable responses due to primary or acquired ICB resistance. Recently, tumor epithelial-to-mesenchymal plasticity (EMP) was identified as a crit...

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Detalles Bibliográficos
Autores principales: Gu, Yuanzhuo, Zhang, Zhengkui, ten Dijke, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10066239/
https://www.ncbi.nlm.nih.gov/pubmed/36823234
http://dx.doi.org/10.1038/s41423-023-00980-8