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Harnessing epithelial-mesenchymal plasticity to boost cancer immunotherapy
Immune checkpoint blockade (ICB) therapy is a powerful option for cancer treatment. Despite demonstrable progress, most patients fail to respond or achieve durable responses due to primary or acquired ICB resistance. Recently, tumor epithelial-to-mesenchymal plasticity (EMP) was identified as a crit...
Autores principales: | Gu, Yuanzhuo, Zhang, Zhengkui, ten Dijke, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10066239/ https://www.ncbi.nlm.nih.gov/pubmed/36823234 http://dx.doi.org/10.1038/s41423-023-00980-8 |
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