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Kynurenine aminotransferase II inhibition promotes sleep and rescues impairments induced by neurodevelopmental insult

Dysregulated sleep is commonly reported in individuals with neuropsychiatric disorders, including schizophrenia (SCZ) and bipolar disorder (BPD). Physiology and pathogenesis of these disorders points to aberrant metabolism, during neurodevelopment and adulthood, of tryptophan via the kynurenine path...

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Detalles Bibliográficos
Autores principales:	Milosavljevic, Snezana, Smith, Andrew K., Wright, Courtney J., Valafar, Homayoun, Pocivavsek, Ana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10066394/ https://www.ncbi.nlm.nih.gov/pubmed/37002202 http://dx.doi.org/10.1038/s41398-023-02399-1

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