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Tau-mediated axonal degeneration is prevented by activation of the Wld(S) pathway

Tauopathy is characterized by neuronal dysfunction and degeneration occurring as a result of changes to the microtubule-associated protein tau. The neuronal changes evident in tauopathy bear striking morphological resemblance to those reported in models of Wallerian degeneration. The mechanisms unde...

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Detalles Bibliográficos
Autores principales:	Stubbs, Katy, Batchelor, Ben, Sivanantharajah, Lovesha, Sealey, Megan, Ramirez-Moreno, Miguel, Ruiz, Eva, Richardson, Brad, Perry, Victor H, Newman, Tracey A, Mudher, Amritpal
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10066515/ https://www.ncbi.nlm.nih.gov/pubmed/37013175 http://dx.doi.org/10.1093/braincomms/fcad052

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