Aryl hydrocarbon receptor activity downstream of IL-10 signaling is required to promote regulatory functions in human dendritic cells

Interleukin (IL)-10 is a main player in peripheral immune tolerance, the physiological mechanism preventing immune reactions to self/harmless antigens. Here, we investigate IL-10-induced molecular mechanisms generating tolerogenic dendritic cells (tolDC) from monocytes. Using genomic studies, we sho...

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Detalles Bibliográficos
Autores principales: Avancini, Daniele, Testori, Alessandro, Fresolone, Lucia, Andolfi, Grazia, Vuono, Michela, Martinelli, Vittorio, Santoni de Sio, Francesca R., Gregori, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10066577/
https://www.ncbi.nlm.nih.gov/pubmed/36870061
http://dx.doi.org/10.1016/j.celrep.2023.112193

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