19n01, a broadly neutralizing antibody against omicron BA.1, BA.2, BA.4/5, and other SARS-CoV-2 variants of concern

This study reports the isolation and characterization of a human monoclonal antibody (mAb) called 19n01. This mAb was isolated by using single-cell RNAseq of B cells from donors infected with the ancestral strain. This mAb possesses a potent and broad capacity to bind and neutralize all previously c...

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Detalles Bibliográficos
Autores principales: García-Vega, Melissa, Melgoza-González, Edgar A., Hernández-Valenzuela, Sofía, Hinojosa-Trujillo, Diana, Reséndiz-Sandoval, Mónica, Llamas-Covarrubias, Mara Anais, Loza-López, Martín, Valenzuela, Olivia, Soto-Gaxiola, Alan, Hernández-Oñate, Miguel A., Mata-Haro, Verónica, Cassaniti, Irene, Sammartino, Josè Camilla, Ferrari, Alessandro, Simonelli, Luca, Pedotti, Mattia, Sun, Rui, Zuo, Fanglei, Baldanti, Fausto, Varani, Luca, Marcotte, Harold, Pan-Hammarström, Qiang, Hernández, Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10066585/
https://www.ncbi.nlm.nih.gov/pubmed/37063467
http://dx.doi.org/10.1016/j.isci.2023.106562

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