An Updated Review on the Metabolite (AM404)-Mediated Central Mechanism of Action of Paracetamol (Acetaminophen): Experimental Evidence and Potential Clinical Impact

Paracetamol remains the recommended first-line option for mild-to-moderate acute pain in general population and particularly in vulnerable populations. Despite its wide use, debate exists regarding the analgesic mechanism of action (MoA) of paracetamol. A growing body of evidence challenged the noti...

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Detalles Bibliográficos
Autores principales: Mallet, Christophe, Desmeules, Jules, Pegahi, Rassa, Eschalier, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10066900/
https://www.ncbi.nlm.nih.gov/pubmed/37016715
http://dx.doi.org/10.2147/JPR.S393809

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10066900/
https://www.ncbi.nlm.nih.gov/pubmed/37016715
http://dx.doi.org/10.2147/JPR.S393809

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