Lack of impact of the ALDH2 rs671 variant on breast cancer development in Japanese BRCA1/2‐mutation carriers

The aldehyde degrading function of the ALDH2 enzyme is impaired by Glu504Lys polymorphisms (rs671, termed A allele), which causes alcohol flushing in east Asians, and elevates the risk of esophageal cancer among habitual drinkers. Recent studies suggested that the ALDH2 variant may lead to higher le...

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Detalles Bibliográficos
Autores principales: Mori, Tomoharu, Okamoto, Yusuke, Mu, Anfeng, Ide, Yoshimi, Yoshimura, Akiyo, Senda, Noriko, Inagaki‐Kawata, Yukiko, Kawashima, Masahiro, Kitao, Hiroyuki, Tokunaga, Eriko, Miyoshi, Yasuo, Ohsumi, Shozo, Tsugawa, Koichiro, Ohta, Tomohiko, Katagiri, Toyomasa, Ohtsuru, Shigeru, Koike, Kaoru, Ogawa, Seishi, Toi, Masakazu, Iwata, Hiroji, Nakamura, Seigo, Matsuo, Keitaro, Takata, Minoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
RESEARCH ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10067083/
https://www.ncbi.nlm.nih.gov/pubmed/36345163
http://dx.doi.org/10.1002/cam4.5430

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