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Histone lysine methyltransferase SETDB2 suppresses NRF2 to restrict tumor progression and modulates chemotherapy sensitivity in lung adenocarcinoma

OBJECTIVE: Aberrant epigenetic remodeling represents a molecular hallmark in lung adenocarcinoma (LUAD). We aim to investigate the biological roles of SETDB2 and its underlying associations with oxidative stress, providing therapeutic targets for individualized treatment of LUAD. METHODS: Differenti...

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Detalles Bibliográficos
Autores principales:	Yuan, Guangda, Hu, Bowen, Ma, Jun, Zhang, Chuanyu, Xie, Hongya, Wei, Tengteng, Yang, Yong, Ni, Bin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	RESEARCH ARTICLES
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10067124/ https://www.ncbi.nlm.nih.gov/pubmed/36504353 http://dx.doi.org/10.1002/cam4.5451

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