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Parametric study of a bubble removing device for hemodialysis

BACKGROUND: This paper sets out to design a device for removing bubbles during the process of hemodialysis. The concept is to guide the bubbles while traveling through the device and eventually the bubbles can be collected. The design focuses on the analysis of various parameters i.e. inlet diameter...

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Autores principales: Chaichudchaval, Poonnapa, Fuangkamonvet, Nunthapat, Piboonlapudom, Supajitra, Chanthasopeephan, Teeranoot
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10067188/
https://www.ncbi.nlm.nih.gov/pubmed/37004140
http://dx.doi.org/10.1186/s42490-023-00069-3
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author Chaichudchaval, Poonnapa
Fuangkamonvet, Nunthapat
Piboonlapudom, Supajitra
Chanthasopeephan, Teeranoot
author_facet Chaichudchaval, Poonnapa
Fuangkamonvet, Nunthapat
Piboonlapudom, Supajitra
Chanthasopeephan, Teeranoot
author_sort Chaichudchaval, Poonnapa
collection PubMed
description BACKGROUND: This paper sets out to design a device for removing bubbles during the process of hemodialysis. The concept is to guide the bubbles while traveling through the device and eventually the bubbles can be collected. The design focuses on the analysis of various parameters i.e. inlet diameter, inlet velocity and size of the pitch. The initial diameters of Models 1 and 2 have thread regions of 6 and 10 mm, respectively. Parameters: Swirl number, Taylor number, Lift coefficient along with pressure field are also implemented. RESULTS: Based on computational fluid dynamics analysis, the bubbles' average maximum equilibrium position for Model 1 reached 1.995 mm, being greater than that of Model 2, which attained 1.833 mm. Then, 16,000 bubbles were released into Model 1 to validate the performance of the model. This number of bubbles is typically found in the dialysis. Thus, it was found that 81.53% of bubbles passed through the radial region of 2.20 ± 0.30 mm. The appropriate collecting plane was at 100 mm, as measured from the inlet position along the axial axis. The Taylor number, Lift coefficient, and Swirl number proved to be significant parameters for describing the movement of the bubbles. Results were based on multiple inlet velocities. It is seen that Model 3, the improved model with unequal pitch, reached a maximum equilibrium position of 2.24 mm. CONCLUSION: Overall, results demonstrated that Model 1 was the best design compared to Models 2 and 3. Model 1 was found capable of guiding the bubbles to the edge location and did not generate extra bubbles. Thus, the parametric study, herein, can be used as a prototype for removing bubbles during the process of hemodialysis.
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spelling pubmed-100671882023-04-03 Parametric study of a bubble removing device for hemodialysis Chaichudchaval, Poonnapa Fuangkamonvet, Nunthapat Piboonlapudom, Supajitra Chanthasopeephan, Teeranoot BMC Biomed Eng Research BACKGROUND: This paper sets out to design a device for removing bubbles during the process of hemodialysis. The concept is to guide the bubbles while traveling through the device and eventually the bubbles can be collected. The design focuses on the analysis of various parameters i.e. inlet diameter, inlet velocity and size of the pitch. The initial diameters of Models 1 and 2 have thread regions of 6 and 10 mm, respectively. Parameters: Swirl number, Taylor number, Lift coefficient along with pressure field are also implemented. RESULTS: Based on computational fluid dynamics analysis, the bubbles' average maximum equilibrium position for Model 1 reached 1.995 mm, being greater than that of Model 2, which attained 1.833 mm. Then, 16,000 bubbles were released into Model 1 to validate the performance of the model. This number of bubbles is typically found in the dialysis. Thus, it was found that 81.53% of bubbles passed through the radial region of 2.20 ± 0.30 mm. The appropriate collecting plane was at 100 mm, as measured from the inlet position along the axial axis. The Taylor number, Lift coefficient, and Swirl number proved to be significant parameters for describing the movement of the bubbles. Results were based on multiple inlet velocities. It is seen that Model 3, the improved model with unequal pitch, reached a maximum equilibrium position of 2.24 mm. CONCLUSION: Overall, results demonstrated that Model 1 was the best design compared to Models 2 and 3. Model 1 was found capable of guiding the bubbles to the edge location and did not generate extra bubbles. Thus, the parametric study, herein, can be used as a prototype for removing bubbles during the process of hemodialysis. BioMed Central 2023-04-01 /pmc/articles/PMC10067188/ /pubmed/37004140 http://dx.doi.org/10.1186/s42490-023-00069-3 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Chaichudchaval, Poonnapa
Fuangkamonvet, Nunthapat
Piboonlapudom, Supajitra
Chanthasopeephan, Teeranoot
Parametric study of a bubble removing device for hemodialysis
title Parametric study of a bubble removing device for hemodialysis
title_full Parametric study of a bubble removing device for hemodialysis
title_fullStr Parametric study of a bubble removing device for hemodialysis
title_full_unstemmed Parametric study of a bubble removing device for hemodialysis
title_short Parametric study of a bubble removing device for hemodialysis
title_sort parametric study of a bubble removing device for hemodialysis
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10067188/
https://www.ncbi.nlm.nih.gov/pubmed/37004140
http://dx.doi.org/10.1186/s42490-023-00069-3
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