The stromal-tumor amplifying STC1-Notch1 feedforward signal promotes the stemness of hepatocellular carcinoma

BACKGROUND: Cancer-associated fibroblasts (CAFs), an important component of the tumor microenvironment (TME), play crucial roles in tumor stemness. It has been shown in various cancer studies that stanniocalcin-1 (STC1) is secreted by CAFs, however, its function in HCC is still not clear. METHODS: T...

Descripción completa

Detalles Bibliográficos
Autores principales: Bai, Shuya, Zhao, Yuchong, Chen, Wei, Peng, Wang, Wang, Yun, Xiong, Si, Aruna, Li, Yanling, Yang, Yilei, Chen, Shiru, Cheng, Bin, Wang, Ronghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10067215/
https://www.ncbi.nlm.nih.gov/pubmed/37004088
http://dx.doi.org/10.1186/s12967-023-04085-8

Ejemplares similares

Ejemplares similares