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A tractable physical model for the yeast polarity predicts epistasis and fitness
Accurate phenotype prediction based on genetic information has numerous societal applications, such as crop design or cellular factories. Epistasis, when biological components interact, complicates modelling phenotypes from genotypes. Here we show an approach to mitigate this complication for polari...
Autores principales: | Daalman, Werner Karl-Gustav, Sweep, Els, Laan, Liedewij |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10067261/ https://www.ncbi.nlm.nih.gov/pubmed/37004720 http://dx.doi.org/10.1098/rstb.2022.0044 |
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