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A tractable physical model for the yeast polarity predicts epistasis and fitness

Accurate phenotype prediction based on genetic information has numerous societal applications, such as crop design or cellular factories. Epistasis, when biological components interact, complicates modelling phenotypes from genotypes. Here we show an approach to mitigate this complication for polari...

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Detalles Bibliográficos
Autores principales: Daalman, Werner Karl-Gustav, Sweep, Els, Laan, Liedewij
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10067261/
https://www.ncbi.nlm.nih.gov/pubmed/37004720
http://dx.doi.org/10.1098/rstb.2022.0044

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