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Epistasis decreases with increasing antibiotic pressure but not temperature

Predicting mutational effects is essential for the control of antibiotic resistance (ABR). Predictions are difficult when there are strong genotype-by-environment (G × E), gene-by-gene (G × G or epistatic) or gene-by-gene-by-environment (G × G × E) interactions. We quantified G × G × E effects in Es...

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Detalles Bibliográficos
Autores principales: Ghenu, Ana-Hermina, Amado, André, Gordo, Isabel, Bank, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10067269/
https://www.ncbi.nlm.nih.gov/pubmed/37004727
http://dx.doi.org/10.1098/rstb.2022.0058