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Epistasis decreases with increasing antibiotic pressure but not temperature
Predicting mutational effects is essential for the control of antibiotic resistance (ABR). Predictions are difficult when there are strong genotype-by-environment (G × E), gene-by-gene (G × G or epistatic) or gene-by-gene-by-environment (G × G × E) interactions. We quantified G × G × E effects in Es...
Autores principales: | Ghenu, Ana-Hermina, Amado, André, Gordo, Isabel, Bank, Claudia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10067269/ https://www.ncbi.nlm.nih.gov/pubmed/37004727 http://dx.doi.org/10.1098/rstb.2022.0058 |
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