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Effects of changing the timing of warfarin administration in combination with fluconazole on prolongation of the PT-INR: a case report

BACKGROUND: Fluconazole (FLCZ) inhibits cytochrome P450 (CYP) 2C9, 2C19, and 3A4 and has a drug-drug interaction that potentiates the effects of warfarin and prolong the prothrombin time-international normalized ratio (PT-INR). Although a drug-drug interaction have been reported between FLCZ and war...

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Detalles Bibliográficos
Autores principales:	Akamatsu, Hayato, Nakagawa, Hiroo, Matsumaru, Ichiro, Hashizume, Junya, Harasawa, Hitomi, Kodama, Yukinobu, Miura, Takashi, Ohyama, Kaname
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Case Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10067283/ https://www.ncbi.nlm.nih.gov/pubmed/37004089 http://dx.doi.org/10.1186/s40780-023-00279-w

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