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A subset of VEGFR‐TKIs activates AMPK in LKB1‐mutant lung cancer

The mutation of tumor suppressor gene liver kinase B1 (LKB1) has a prevalence of about 20% in non–small cell lung cancer (NSCLC). LKB1‐mutant lung cancer is characterized by enhanced aggressiveness and immune escape and is associated with poor prognosis. Therefore, it is urgent to develop effective...

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Detalles Bibliográficos
Autores principales: Yang, Lujie, Zhang, Qin, Xiong, Yanli, Dang, Zhaoqian, Xiao, He, Chen, Qian, Dai, Xiaoyan, Zhang, Lei, Zhu, Jianwu, Wang, Dong, Li, Mengxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10067398/
https://www.ncbi.nlm.nih.gov/pubmed/36459496
http://dx.doi.org/10.1111/cas.15677

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