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Metabolic adaptations of cancer in extreme tumor microenvironments
Cancer cells are highly heterogeneous to adapt to extreme tumor microenvironments (TMEs). TMEs challenge cancer cells via hypoxia, nutrition starvation, and acidic pH, promoting invasion and metastasis concomitant with genetic, epigenetic, and metabolic alterations. Metabolic adaptation to an extrem...
Autores principales: | Nakahara, Ryuichi, Maeda, Keisuke, Aki, Sho, Osawa, Tsuyoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10067430/ https://www.ncbi.nlm.nih.gov/pubmed/36630222 http://dx.doi.org/10.1111/cas.15722 |
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