Cargando…

Tellu – an object-detector algorithm for automatic classification of intestinal organoids

Intestinal epithelial organoids recapitulate many of the in vivo features of the intestinal epithelium, thus representing excellent research models. Morphology of the organoids based on light-microscopy images is used as a proxy to assess the biological state of the intestinal epithelium. Currently,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Domènech-Moreno, Eva, Brandt, Anders, Lemmetyinen, Toni T., Wartiovaara, Linnea, Mäkelä, Tomi P., Ollila, Saara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists Ltd 2023
Materias:	Resource Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10067441/ https://www.ncbi.nlm.nih.gov/pubmed/36804687 http://dx.doi.org/10.1242/dmm.049756

Ejemplares similares

Fibroblast-derived EGF ligand neuregulin 1 induces fetal-like reprogramming of the intestinal epithelium without supporting tumorigenic growth
por: Lemmetyinen, Toni T., et al.
Publicado: (2023)

Gruffi: an algorithm for computational removal of stressed cells from brain organoid transcriptomic datasets
por: Vértesy, Ábel, et al.
Publicado: (2022)

Long‐term expanding human airway organoids for disease modeling
por: Sachs, Norman, et al.
Publicado: (2019)

Simultaneous high-efficiency base editing and reprogramming of patient fibroblasts
por: Jalil, Sami, et al.
Publicado: (2021)

Cell Types of the Human Retina and Its Organoids at Single-Cell Resolution
por: Cowan, Cameron S., et al.
Publicado: (2020)

Disease Modeling and Gene Therapy of Copper Storage Disease in Canine Hepatic Organoids
por: Nantasanti, Sathidpak, et al.
Publicado: (2015)

Self-Renewing Trophoblast Organoids Recapitulate the Developmental Program of the Early Human Placenta
por: Haider, Sandra, et al.
Publicado: (2018)

Nonadhesive Alginate Hydrogels Support Growth of Pluripotent Stem Cell-Derived Intestinal Organoids
por: Capeling, Meghan M., et al.
Publicado: (2019)

Charting human development using a multi-endodermal organ atlas and organoid models
por: Yu, Qianhui, et al.
Publicado: (2021)

Vascularized human cortical organoids (vOrganoids) model cortical development in vivo
por: Shi, Yingchao, et al.
Publicado: (2020)

A human breast cancer-derived xenograft and organoid platform for drug discovery and precision oncology
por: Guillen, Katrin P., et al.
Publicado: (2022)

A Refined Culture System for Human Induced Pluripotent Stem Cell-Derived Intestinal Epithelial Organoids
por: Takahashi, Yu, et al.
Publicado: (2017)

Accelerated and Improved Differentiation of Retinal Organoids from Pluripotent Stem Cells in Rotating-Wall Vessel Bioreactors
por: DiStefano, Tyler, et al.
Publicado: (2017)

Stable expansion of high‐grade serous ovarian cancer organoids requires a low‐Wnt environment
por: Hoffmann, Karen, et al.
Publicado: (2020)

Automatic identification of small molecules that promote cell conversion and reprogramming
por: Napolitano, Francesco, et al.
Publicado: (2021)

Aggregation of cryopreserved mid-hindgut endoderm for more reliable and reproducible hPSC-derived small intestinal organoid generation
por: Pitstick, Amy L., et al.
Publicado: (2022)

The Microfluidic Environment Reveals a Hidden Role of Self-Organizing Extracellular Matrix in Hepatic Commitment and Organoid Formation of hiPSCs
por: Michielin, Federica, et al.
Publicado: (2020)

Differentiation of brain and retinal organoids from confluent cultures of pluripotent stem cells connected by nerve-like axonal projections of optic origin
por: Fernando, Milan, et al.
Publicado: (2022)

ORTHOSCOPE: An Automatic Web Tool for Phylogenetically Inferring Bilaterian Orthogroups with User-Selected Taxa
por: Inoue, Jun, et al.
Publicado: (2019)

Human Pluripotent Stem Cell-Derived Intestinal Organoids Model SARS-CoV-2 Infection Revealing a Common Epithelial Inflammatory Response
por: Mithal, Aditya, et al.
Publicado: (2021)

MitoFish and MitoAnnotator: A Mitochondrial Genome Database of Fish with an Accurate and Automatic Annotation Pipeline
por: Iwasaki, Wataru, et al.
Publicado: (2013)

An automatic pipeline for the design of irreversible derivatives identifies a potent SARS-CoV-2 M(pro) inhibitor
por: Zaidman, Daniel, et al.
Publicado: (2021)

MOrgAna: accessible quantitative analysis of organoids with machine learning
por: Gritti, Nicola, et al.
Publicado: (2021)

Trophoblast organoids with physiological polarity model placental structure and function
por: Yang, Liheng, et al.
Publicado: (2023)

Efficient genetic editing of human intestinal organoids using ribonucleoprotein-based CRISPR
por: Skoufou-Papoutsaki, Nefeli, et al.
Publicado: (2023)

Proactive functional classification of all possible missense single-nucleotide variants in KCNQ4
por: Zheng, Honglan, et al.
Publicado: (2022)

Episodic live imaging of cone photoreceptor maturation in GNAT2-EGFP retinal organoids
por: Bai, Jinlun, et al.
Publicado: (2023)

Methylome Analysis of Human Bone Marrow MSCs Reveals Extensive Age- and Culture-Induced Changes at Distal Regulatory Elements
por: Pasumarthy, Kalyan K., et al.
Publicado: (2017)

Quantitative Cell Cycle Analysis Based on an Endogenous All-in-One Reporter for Cell Tracking and Classification
por: Zerjatke, Thomas, et al.
Publicado: (2017)

Robust circadian rhythms in organoid cultures from PERIOD2::LUCIFERASE mouse small intestine
por: Moore, Sean R., et al.
Publicado: (2014)

A new pipeline for pathophysiological analysis of the mammary gland based on organoid transplantation and organ clearing
por: Lagoutte, Emilie, et al.
Publicado: (2020)

Human striatal organoids derived from pluripotent stem cells recapitulate striatal development and compartments
por: Chen, Xinyu, et al.
Publicado: (2022)

SUMOylation of AMPKα1 by PIAS4 specifically regulates mTORC1 signalling
por: Yan, Yan, et al.
Publicado: (2015)

γ-TEMPy: Simultaneous Fitting of Components in 3D-EM Maps of Their Assembly Using a Genetic Algorithm
por: Pandurangan, Arun Prasad, et al.
Publicado: (2015)

Efficient and error-free fluorescent gene tagging in human organoids without double-strand DNA cleavage
por: Bollen, Yannik, et al.
Publicado: (2022)

High-content phenotyping of Parkinson's disease patient stem cell-derived midbrain dopaminergic neurons using machine learning classification
por: Vuidel, Aurore, et al.
Publicado: (2022)

Automatic inference of demographic parameters using generative adversarial networks
por: Wang, Zhanpeng, et al.
Publicado: (2021)

Modeling diverse genetic subtypes of lung adenocarcinoma with a next-generation alveolar type 2 organoid platform
por: Naranjo, Santiago, et al.
Publicado: (2022)

Simultaneous isolation of hormone receptor–positive breast cancer organoids and fibroblasts reveals stroma-mediated resistance mechanisms
por: Hogstrom, Jenny M., et al.
Publicado: (2023)

Pneumolysin promotes host cell necroptosis and bacterial competence during pneumococcal meningitis as shown by whole-animal dual RNA-seq
por: Jim, Kin Ki, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_jjkio3jc4nte4c6pslje5d6d80