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A study of somatic BRCA variants and their putative effect on protein properties in malignant mesothelioma

OBJECTIVES: The aim of this study is to analyze the prevalence of somatic mutations in BRCA1 and BRCA2 in malignant mesothelioma and their putative impact on protein properties. METHODS: Eighteen cases of malignant mesothelioma were retrieved from the archives and for next generation sequencing anal...

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Detalles Bibliográficos
Autores principales:	Krishnamurthy, Kritika, Oh, Kei Shing, Alghamdi, Sarah, Sriganeshan, Vathany, Poppiti, Robert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	De Gruyter 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10067552/ https://www.ncbi.nlm.nih.gov/pubmed/37020472 http://dx.doi.org/10.1515/pp-2023-0003

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