Cargando…

Acute effect of antiseizure drugs on background oscillations in Scn1a (A1783V) Dravet syndrome mouse model

Dravet syndrome (Dravet) is a rare and severe form of developmental epileptic encephalopathy. Antiseizure medications (ASMs) for Dravet patients include valproic acid (VA) or clobazam (CLB), with or without stiripentol (STP), while sodium channel blockers like carbamazepine (CBZ) or lamotrigine (LTG...

Descripción completa

Detalles Bibliográficos
Autores principales:	Quinn, Shir, Brusel, Marina, Ovadia, Mor, Rubinstein, Moran
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10067575/ https://www.ncbi.nlm.nih.gov/pubmed/37021051 http://dx.doi.org/10.3389/fphar.2023.1118216

Ejemplares similares

Dravet Variant SCN1A(A1783V) Impairs Interneuron Firing Predominantly by Altered Channel Activation
por: Layer, Nikolas, et al.
Publicado: (2021)

Heat-induced seizures, premature mortality, and hyperactivity in a novel Scn1a nonsense model for Dravet syndrome
por: Mavashov, Anat, et al.
Publicado: (2023)

Functional Investigation of a Neuronal Microcircuit in the CA1 Area of the Hippocampus Reveals Synaptic Dysfunction in Dravet Syndrome Mice
por: Almog, Yael, et al.
Publicado: (2022)

Efficacy and safety of adjunctive antiseizure medications for dravet syndrome: A systematic review and network meta-analysis
por: Wu, Jianhua, et al.
Publicado: (2022)

The Heat Sensing Trpv1 Receptor Is Not a Viable Anticonvulsant Drug Target in the Scn1a (+/−) Mouse Model of Dravet Syndrome
por: Satpute Janve, Vaishali, et al.
Publicado: (2021)

Combined Antiseizure Efficacy of Cannabidiol and Clonazepam in a Conditional Mouse Model of Dravet Syndrome
por: Chuang, Shu-Hui, et al.
Publicado: (2021)

Ictal vocalizations in the Scn1a (+/−) mouse model of Dravet syndrome
por: Anderson, Lyndsey L., et al.
Publicado: (2023)

Drug repurposing for Dravet syndrome in scn1Lab (−/−) mutant zebrafish
por: Sourbron, Jo, et al.
Publicado: (2019)

Delayed maturation of GABAergic signaling in the Scn1a and Scn1b mouse models of Dravet Syndrome
por: Yuan, Yukun, et al.
Publicado: (2019)

Scn8a Antisense Oligonucleotide Is Protective in Mouse Models of SCN8A Encephalopathy and Dravet Syndrome
por: Lenk, Guy M., et al.
Publicado: (2020)

Transfer of SCN1A to the brain of adolescent mouse model of Dravet syndrome improves epileptic, motor, and behavioral manifestations
por: Mora-Jimenez, Lucia, et al.
Publicado: (2021)

Perampanel Reduces Hyperthermia-Induced Seizures in Dravet Syndrome Mouse Model
por: Ho, Shih-Yin, et al.
Publicado: (2021)

A retrospective review of changes and challenges in the use of antiseizure medicines in Dravet syndrome in Norway
por: Heger, Katrine, et al.
Publicado: (2020)

Development of an antiseizure drug screening platform for Dravet syndrome at the NINDS contract site for the Epilepsy Therapy Screening Program
por: Pernici, Chelsea D., et al.
Publicado: (2021)

In vivo, in vitro and in silico correlations of four de novo SCN1A missense mutations
por: Nissenkorn, Andreea, et al.
Publicado: (2019)

Efficacy of Stiripentol in Dravet Syndrome with or without SCN1A Mutations
por: Cho, Min Jung, et al.
Publicado: (2018)

Dravet syndrome: a new causative SCN1A mutation?
por: Poryo, Martin, et al.
Publicado: (2017)

Behavioral Comorbidities and Drug Treatments in a Zebrafish scn1lab Model of Dravet Syndrome
por: Grone, Brian P., et al.
Publicado: (2017)

Viral vector–mediated expression of Na(V)1.1, after seizure onset, reduces epilepsy in mice with Dravet syndrome
por: Fadila, Saja, et al.
Publicado: (2023)

Preclinical Animal Models for Dravet Syndrome: Seizure Phenotypes, Comorbidities and Drug Screening
por: Griffin, Aliesha, et al.
Publicado: (2018)

SCN1B and SCN2B gene variants analysis in dravet syndrome patients: Analysis of 22 cases
por: Gong, Jiao-E., et al.
Publicado: (2019)

Dravet Syndrome in Lebanon: First Report on Cases with SCN1A Mutations
por: Alame, Saada, et al.
Publicado: (2019)

Augmented Reticular Thalamic Bursting and Seizures in Scn1a-Dravet Syndrome
por: Ritter-Makinson, Stefanie, et al.
Publicado: (2019)

Augmented Reticular Thalamic Bursting and Seizures in Scn1a-Dravet Syndrome
por: Ritter-Makinson, Stefanie, et al.
Publicado: (2019)

TANGO With SCN1A: Can This Molecular Dance Defeat Dravet Syndrome?
por: Wagnon, Jacy L.
Publicado: (2020)

Drug screening in Scn1a zebrafish mutant identifies clemizole as a potential Dravet Syndrome treatment
por: Baraban, Scott C., et al.
Publicado: (2013)

Identification of SCN1A and PCDH19 Mutations in Chinese Children with Dravet Syndrome
por: Kwong, Anna Ka-Yee, et al.
Publicado: (2012)

Morphometry and network-based atrophy patterns in SCN1A-related Dravet syndrome
por: Lenge, Matteo, et al.
Publicado: (2023)

Neuropharmacology of Antiseizure Drugs
por: Hakami, Tahir
Publicado: (2021)

La Europa revolucionaria, 1783-1815 /
por: Rudé, George F. E.
Publicado: (1974)

The medical practitioners of provincial England in 1783.
por: Lane, J
Publicado: (1984)

John Syng Dorsey (1783-1818)
por: Middleton, William Shainline
Publicado: (1930)

The American Medical Profession, 1783-1850
Publicado: (1936)

Inhibitory synaptic transmission is impaired at higher extracellular Ca(2+) concentrations in Scn1a(+/−) mouse model of Dravet syndrome
por: Uchino, Kouya, et al.
Publicado: (2021)

Scn1a gene reactivation after symptom onset rescues pathological phenotypes in a mouse model of Dravet syndrome
por: Valassina, Nicholas, et al.
Publicado: (2022)

Cannabidiol Increases Seizure Resistance and Improves Behavior in an Scn8a Mouse Model
por: Shapiro, Lindsey, et al.
Publicado: (2022)

SCN1A Gene Mutation and Adaptive Functioning in 18 Vietnamese Children with Dravet Syndrome
por: Do, Thi Thu Hang, et al.
Publicado: (2017)

SCN1A Mutation—Beyond Dravet Syndrome: A Systematic Review and Narrative Synthesis
por: Ding, Jiangwei, et al.
Publicado: (2021)

Multimodal Analysis of SCN1A Missense Variants Improves Interpretation of Clinically Relevant Variants in Dravet Syndrome
por: Gonsales, Marina C., et al.
Publicado: (2019)

Phenotype-Based Screening of Synthetic Cannabinoids in a Dravet Syndrome Zebrafish Model
por: Griffin, Aliesha, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_5tptc1ehp69nqcqjsbnv1clep7