Identification of a peptide ligand for human ALDH3A1 through peptide phage display: Prediction and characterization of protein interaction sites and inhibition of ALDH3A1 enzymatic activity

Aldehyde dehydrogenase 3A1 (ALDH3A1) by oxidizing medium chain aldehydes to their corresponding carboxylic acids, is involved in the detoxification of toxic byproducts and is considered to play an important role in antioxidant cellular defense. ALDH3A1 has been implicated in various other functions...

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Detalles Bibliográficos
Autores principales: Voulgaridou, Georgia-Persephoni, Theologidis, Vasileios, Xanthis, Vasileios, Papagiannaki, Eleni, Tsochantaridis, Ilias, Fadouloglou, Vasiliki E., Pappa, Aglaia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10067601/
https://www.ncbi.nlm.nih.gov/pubmed/37021113
http://dx.doi.org/10.3389/fmolb.2023.1161111

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