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MiR-122-5p regulates the mevalonate pathway by targeting p53 in non-small cell lung cancer

The 5-year survival rate of non-small cell lung cancer (NSCLC) patients is very low. MicroRNAs (miRNAs) are involved in the occurrence of NSCLC. miR-122-5p interacts with wild-type p53 (wtp53), and wtp53 affects tumor growth by inhibiting the mevalonate (MVA) pathway. Therefore, this study aimed to...

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Detalles Bibliográficos
Autores principales: Zheng, Yu-kun, Zhou, Zhong-shi, Wang, Guang-zhong, Tu, Ji-yuan, Cheng, Huan-bo, Ma, Shang-zhi, Ke, Chang, Wang, Yan, Jian, Qi-pan, Shu, Yu-hang, Wu, Xiao-wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10067850/
https://www.ncbi.nlm.nih.gov/pubmed/37005437
http://dx.doi.org/10.1038/s41419-023-05761-9

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