Sialidases and fucosidases of Akkermansia muciniphila are crucial for growth on mucin and nutrient sharing with mucus-associated gut bacteria

The mucolytic human gut microbiota specialist Akkermansia muciniphila is proposed to boost mucin-secretion by the host, thereby being a key player in mucus turnover. Mucin glycan utilization requires the removal of protective caps, notably fucose and sialic acid, but the enzymatic details of this pr...

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Detalles Bibliográficos
Autores principales: Shuoker, Bashar, Pichler, Michael J., Jin, Chunsheng, Sakanaka, Hiroka, Wu, Haiyang, Gascueña, Ana Martínez, Liu, Jining, Nielsen, Tine Sofie, Holgersson, Jan, Nordberg Karlsson, Eva, Juge, Nathalie, Meier, Sebastian, Morth, Jens Preben, Karlsson, Niclas G., Abou Hachem, Maher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10067855/
https://www.ncbi.nlm.nih.gov/pubmed/37005422
http://dx.doi.org/10.1038/s41467-023-37533-6

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