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Time series clustering of T cell subsets dissects heterogeneity in immune reconstitution and clinical outcomes among MUD-HCT patients receiving ATG or PTCy

INTRODUCTION: Anti-T-lymphocyte globulin (ATG) or post-transplant cyclophosphamide (PTCy) prevent graft-versus-host disease (GVHD) after hematopoietic cell transplantation (HCT), yet individual patients benefit differentially. METHODS: Given the sparse comparative data on the impact of cellular immu...

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Detalles Bibliográficos
Autores principales: Leserer, Saskia, Graf, Theresa, Franke, Martina, Bogdanov, Rashit, Arrieta-Bolaños, Esteban, Buttkereit, Ulrike, Leimkühler, Nils, Fleischhauer, Katharina, Reinhardt, Hans Christian, Beelen, Dietrich W., Turki, Amin T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10067907/
https://www.ncbi.nlm.nih.gov/pubmed/37020562
http://dx.doi.org/10.3389/fimmu.2023.1082727