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Molecular pathways identified from single nucleotide polymorphisms demonstrate mechanistic differences in systemic lupus erythematosus patients of Asian and European ancestry

Systemic lupus erythematosus (SLE) is a multi-organ autoimmune disorder with a prominent genetic component. Individuals of Asian-Ancestry (AsA) disproportionately experience more severe SLE compared to individuals of European-Ancestry (EA), including increased renal involvement and tissue damage. Ho...

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Detalles Bibliográficos
Autores principales: Owen, Katherine A., Bell, Kristy A., Price, Andrew, Bachali, Prathyusha, Ainsworth, Hannah, Marion, Miranda C., Howard, Timothy D., Langefeld, Carl D., Shen, Nan, Yazdany, Jinoos, Dall’era, Maria, Grammer, Amrie C., Lipsky, Peter E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10067935/
https://www.ncbi.nlm.nih.gov/pubmed/37005464
http://dx.doi.org/10.1038/s41598-023-32569-6

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