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Molecular pathways identified from single nucleotide polymorphisms demonstrate mechanistic differences in systemic lupus erythematosus patients of Asian and European ancestry
Systemic lupus erythematosus (SLE) is a multi-organ autoimmune disorder with a prominent genetic component. Individuals of Asian-Ancestry (AsA) disproportionately experience more severe SLE compared to individuals of European-Ancestry (EA), including increased renal involvement and tissue damage. Ho...
Autores principales: | Owen, Katherine A., Bell, Kristy A., Price, Andrew, Bachali, Prathyusha, Ainsworth, Hannah, Marion, Miranda C., Howard, Timothy D., Langefeld, Carl D., Shen, Nan, Yazdany, Jinoos, Dall’era, Maria, Grammer, Amrie C., Lipsky, Peter E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10067935/ https://www.ncbi.nlm.nih.gov/pubmed/37005464 http://dx.doi.org/10.1038/s41598-023-32569-6 |
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