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A PI3K-calcium-Nox axis primes leukocyte Nrf2 to boost immune resilience and limit collateral damage
Phagosomal reactive oxygen species (ROS) are strategically employed by leukocytes to kill internalized pathogens and degrade cellular debris. Nevertheless, uncontrolled oxidant bursts could cause serious collateral damage to phagocytes or other host tissues, potentially accelerating aging and compro...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Rockefeller University Press
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10067972/ https://www.ncbi.nlm.nih.gov/pubmed/36995284 http://dx.doi.org/10.1083/jcb.202203062 |