Nitrous Oxide Inhalation Sedation Rapid Analgesia in Dentistry: An Overview of Technique, Objectives, Indications, Advantages, Monitoring, and Safety Profile

Nitrous oxide inhalation sedation (NOIS) has been the backbone of anxiety alleviation in dentistry for a long time. Advantages of nitrous oxide (N(2)O) include anxiolysis, mild analgesia, and amnesia. It also has the ability to raise the patient pain threshold, providing rapid analgesia (RA), thus enhancing the action of any local anesthesia used. This paper describes the technique of NOIS in detail and highlights its objectives, advantages, indications, monitoring, and safety profile. Other than the specialty of pediatric dentistry, this paper also highlights the applications and merits of NOIS in adult, geriatric, and special healthcare needs dentistry. Away from dentistry, it also brings to light the multidisciplinary applications of NOIS in other medical streams. This review could be a valuable interpretation on the present position of N(2)O sedation in dentistry and a valuable starting point for future perspectives. HOW TO CITE THIS ARTICLE: Khinda V, Rao D, Singh Sodhi SP. Nitrous Oxide Inhalation Sedation Rapid Analgesia in Dentistry: An Overview of Technique, Objectives, Indications, Advantages, Monitoring, and Safety Profile. Int J Clin Pediatr Dent 2023;16(1):131-138.