An optimized workflow for MS-based quantitative proteomics of challenging clinical bronchoalveolar lavage fluid (BALF) samples

BACKGROUND: Clinical bronchoalveolar lavage fluid (BALF) samples are rich in biomolecules, including proteins, and useful for molecular studies of lung health and disease. However, mass spectrometry (MS)-based proteomic analysis of BALF is challenged by the dynamic range of protein abundance, and po...

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Detalles Bibliográficos
Autores principales: Weise, Danielle O., Kruk, Monica E., Higgins, LeeAnn, Markowski, Todd W., Jagtap, Pratik D., Mehta, Subina, Mickelson, Alan, Parker, Laurie L., Wendt, Christine H., Griffin, Timothy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10068177/
https://www.ncbi.nlm.nih.gov/pubmed/37005570
http://dx.doi.org/10.1186/s12014-023-09404-1

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