Obesity defined molecular endotypes in the synovium of patients with osteoarthritis provides a rationale for therapeutic targeting of fibroblast subsets

BACKGROUND: Osteoarthritis (OA), a multifaceted condition, poses a significant challenge for the successful clinical development of therapeutics due to heterogeneity. However, classifying molecular endotypes of OA pathogenesis could provide invaluable phenotype‐directed routes for stratifying subgro...

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Detalles Bibliográficos
Autores principales: Wijesinghe, Susanne N., Badoume, Amel, Nanus, Dominika E., Sharma‐Oates, Archana, Farah, Hussein, Certo, Michelangelo, Alnajjar, Fawzeyah, Davis, Edward T., Mauro, Claudio, Lindsay, Mark A., Jones, Simon W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10068310/
https://www.ncbi.nlm.nih.gov/pubmed/37006170
http://dx.doi.org/10.1002/ctm2.1232

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