Stress‐dependent macromolecular crowding in the mitochondrial matrix

Macromolecules of various sizes induce crowding of the cellular environment. This crowding impacts on biochemical reactions by increasing solvent viscosity, decreasing the water‐accessible volume and altering protein shape, function, and interactions. Although mitochondria represent highly protein‐r...

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Detalles Bibliográficos
Autores principales: Bulthuis, Elianne P, Dieteren, Cindy E J, Bergmans, Jesper, Berkhout, Job, Wagenaars, Jori A, van de Westerlo, Els M A, Podhumljak, Emina, Hink, Mark A, Hesp, Laura F B, Rosa, Hannah S, Malik, Afshan N, Lindert, Mariska Kea‐te, Willems, Peter H G M, Gardeniers, Han J G E, den Otter, Wouter K, Adjobo‐Hermans, Merel J W, Koopman, Werner J H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10068333/
https://www.ncbi.nlm.nih.gov/pubmed/36825437
http://dx.doi.org/10.15252/embj.2021108533

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