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Cytosolic domain regulates the calcium sensitivity and surface expression of BEST1 channels in the HEK293 cells

BEST family is a class of Ca(2+)-activated Cl-channels evolutionary well conserved from bacteria to human. The human BEST paralogs (BEST1-BEST4) share significant amino acid sequence homology in the N-terminal region, which forms the transmembrane helicases and contains the direct calcium-binding si...

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Detalles Bibliográficos
Autores principales: Kim, Kwon Woo, Hwang, Junmo, Kim, Dong-Hyun, Park, Hyungju, Lim, Hyun-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10068347/
https://www.ncbi.nlm.nih.gov/pubmed/36593105
http://dx.doi.org/10.5483/BMBRep.2022-0170