Development of an optimized and practical pharmacokinetics/pharmacodynamics analysis method for aztreonam/nacubactam against carbapenemase-producing K. pneumoniae

BACKGROUND: Nacubactam, a new β-lactamase inhibitor with antibacterial activity, is being developed as a single drug to be co-administered with cefepime or aztreonam. However, determining pharmacokinetics/pharmacodynamics (PK/PD) parameters in β-lactam/β-lactamase inhibitor combinations remains chal...

Descripción completa

Detalles Bibliográficos
Autores principales: Igarashi, Yuki, Takemura, Wataru, Liu, Xiaoxi, Kojima, Nana, Morita, Takumi, Chuang, Victor Tuan Giam, Enoki, Yuki, Taguchi, Kazuaki, Matsumoto, Kazuaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10068424/
https://www.ncbi.nlm.nih.gov/pubmed/36775998
http://dx.doi.org/10.1093/jac/dkad033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10068424/
https://www.ncbi.nlm.nih.gov/pubmed/36775998
http://dx.doi.org/10.1093/jac/dkad033

Ejemplares similares