Liquid Biopsy of Cerebrospinal Fluid Enables Selective Profiling of Glioma Molecular Subtypes at First Clinical Presentation

PURPOSE: Current glioma diagnostic guidelines call for molecular profiling to stratify patients into prognostic and treatment subgroups. In case the tumor tissue is inaccessible, cerebrospinal fluid (CSF) has been proposed as a reliable tumor DNA source for liquid biopsy. We prospectively investigat...

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Detalles Bibliográficos
Autores principales: Orzan, Francesca, De Bacco, Francesca, Lazzarini, Elisabetta, Crisafulli, Giovanni, Gasparini, Alessandra, Dipasquale, Angelo, Barault, Ludovic, Macagno, Marco, Persico, Pasquale, Pessina, Federico, Bono, Beatrice, Giordano, Laura, Zeppa, Pietro, Melcarne, Antonio, Cassoni, Paola, Garbossa, Diego, Santoro, Armando, Comoglio, Paolo M., Indraccolo, Stefano, Simonelli, Matteo, Boccaccio, Carla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Precision Medicine and Imaging
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10068436/
https://www.ncbi.nlm.nih.gov/pubmed/36648487
http://dx.doi.org/10.1158/1078-0432.CCR-22-2903

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