Genomic Instability and Protumoral Inflammation Are Associated with Primary Resistance to Anti–PD-1 + Antiangiogenesis in Malignant Pleural Mesothelioma

Cancer immunotherapy combinations have recently been shown to improve the overall survival of advanced mesotheliomas, especially for patients responding to those treatments. We aimed to characterize the biological correlates of malignant pleural mesotheliomas’ primary resistance to immunotherapy and...

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Detalles Bibliográficos
Autores principales: Danlos, François-Xavier, Texier, Matthieu, Job, Bastien, Mouraud, Severine, Cassard, Lydie, Baldini, Capucine, Varga, Andrea, Yurchenko, Andrey A., Rabeau, Audrey, Champiat, Stéphane, Letourneur, Diane, Bredel, Delphine, Susini, Sandrine, Blum, Yuna, Parpaleix, Aurelien, Parlavecchio, Cedric, Tselikas, Lambros, Fahrner, Jean-Eudes, Goubet, Anne-Gaelle, Rouanne, Mathieu, Rafie, Saloomeh, Abbassi, Alae, Kasraoui, Ines, Breckler, Marie, Farhane, Siham, Ammari, Samy, Laghouati, Salim, Gazzah, Anas, Lacroix, Ludovic, Besse, Benjamin, Droin, Nathalie, Deloger, Marc, Cotteret, Sophie, Adam, Julien, Zitvogel, Laurence, Nikolaev, Sergey I., Chaput, Nathalie, Massard, Christophe, Soria, Jean-Charles, Gomez-Roca, Carlos, Zalcman, Gerard, Planchard, David, Marabelle, Aurelien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10068454/
https://www.ncbi.nlm.nih.gov/pubmed/36669143
http://dx.doi.org/10.1158/2159-8290.CD-22-0886

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