Oxidative stress induces MUC5AC expression through mitochondrial damage‐dependent STING signaling in human bronchial epithelial cells

Oxidative stress increases the production of the predominant mucin MUC5AC in airway epithelial cells and is implicated in the pathogenesis of bronchial asthma and chronic obstructive pulmonary disease. Oxidative stress impairs mitochondria, releasing mitochondrial DNA into the cytoplasm and inducing...

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Detalles Bibliográficos
Autores principales: Nishida, Yutaka, Yagi, Hisako, Ota, Masaya, Tanaka, Atsushi, Sato, Koichiro, Inoue, Takaharu, Yamada, Satoshi, Arakawa, Naoya, Ishige, Takashi, Kobayashi, Yasuko, Arakawa, Hirokazu, Takizawa, Takumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10068767/
https://www.ncbi.nlm.nih.gov/pubmed/37020748
http://dx.doi.org/10.1096/fba.2022-00081

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10068767/
https://www.ncbi.nlm.nih.gov/pubmed/37020748
http://dx.doi.org/10.1096/fba.2022-00081

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