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Oxidative stress induces MUC5AC expression through mitochondrial damage‐dependent STING signaling in human bronchial epithelial cells
Oxidative stress increases the production of the predominant mucin MUC5AC in airway epithelial cells and is implicated in the pathogenesis of bronchial asthma and chronic obstructive pulmonary disease. Oxidative stress impairs mitochondria, releasing mitochondrial DNA into the cytoplasm and inducing...
Autores principales: | Nishida, Yutaka, Yagi, Hisako, Ota, Masaya, Tanaka, Atsushi, Sato, Koichiro, Inoue, Takaharu, Yamada, Satoshi, Arakawa, Naoya, Ishige, Takashi, Kobayashi, Yasuko, Arakawa, Hirokazu, Takizawa, Takumi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10068767/ https://www.ncbi.nlm.nih.gov/pubmed/37020748 http://dx.doi.org/10.1096/fba.2022-00081 |
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