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Engineering Saccharomyces cerevisiae for the de novo Production of Halogenated Tryptophan and Tryptamine Derivatives

The indole scaffold is a recurring structure in multiple bioactive heterocycles and natural products. Substituted indoles like the amino acid tryptophan serve as a precursor for a wide range of natural products with pharmaceutical or agrochemical applications. Inspired by the versatility of these co...

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Detalles Bibliográficos
Autores principales: Milne, Nicholas, Sáez‐Sáez, Javier, Nielsen, Annette Munch, Dyekjær, Jane Dannow, Rago, Daniela, Kristensen, Mette, Wulff, Tune, Borodina, Irina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10068768/
https://www.ncbi.nlm.nih.gov/pubmed/36929157
http://dx.doi.org/10.1002/open.202200266