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Impact of various buffers and weak bases on lysosomal and intracellular pH: Implications for infectivity of SARS‐CoV‐2
Acidification of the cellular lysosome is an important factor in infection of mammalian cells by SARS‐CoV‐2. Therefore, raising the pH of the lysosome would theoretically be beneficial in prevention or treatment of SARS‐CoV‐2 infection. Sodium bicarbonate, carbicarb, and THAM are buffers that can be...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10068769/ https://www.ncbi.nlm.nih.gov/pubmed/37020747 http://dx.doi.org/10.1096/fba.2022-00062 |