WDFY4 deficiency in NOD mice ameliorates autoimmune diabetes and insulitis

The events that initiate autoimmune diabetes in nonobese diabetic (NOD) mice remain poorly understood. CD4(+) and CD8(+) T cells are both required to develop disease, but their relative roles in initiating disease are unclear. To test whether CD4(+) T cell infiltration into islets requires damage to...

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Detalles Bibliográficos
Autores principales: Ferris, Stephen T., Liu, Tiantian, Chen, Jing, Ohara, Ray A., Ou, Feiya, Wu, Renee, Kim, Sunkyung, Murphy, Theresa L., Murphy, Kenneth M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10068798/
https://www.ncbi.nlm.nih.gov/pubmed/36940342
http://dx.doi.org/10.1073/pnas.2219956120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10068798/
https://www.ncbi.nlm.nih.gov/pubmed/36940342
http://dx.doi.org/10.1073/pnas.2219956120

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