Cargando…

MALAT1 knockdown alleviates the pyroptosis of microglias in diabetic cerebral ischemia via regulating STAT1 mediated NLRP3 transcription

BACKGROUND: Dysregulated long non-coding RNAs participate in the development of diabetic cerebral ischemia. This study aimed to investigate the underlying mechanism of lncRNA MALAT1 in diabetic cerebral ischemia. METHOD: Middle cerebral artery occlusion (MCAO) was performed to establish diabetic cer...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhao, Nan, Hua, Wei, Liu, Qi, Wang, Yueying, Liu, Zhiyi, Jin, Sinan, Wang, Benshuai, Pang, Yuxin, Qi, Jiping, Song, Yuejia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10069069/ https://www.ncbi.nlm.nih.gov/pubmed/37013491 http://dx.doi.org/10.1186/s10020-023-00637-2

Ejemplares similares

Dapagliflozin alleviates renal podocyte pyroptosis via regulation of the HO‑1/NLRP3 axis
por: Zhang, Zhenwang, et al.
Publicado: (2023)

Calycosin Alleviates Doxorubicin-Induced Cardiotoxicity and Pyroptosis by Inhibiting NLRP3 Inflammasome Activation
por: Zhang, Lei, et al.
Publicado: (2022)

miR-183-5p alleviates early injury after intracerebral hemorrhage by inhibiting heme oxygenase-1 expression
por: Wang, Yu, et al.
Publicado: (2020)

Icariin alleviates osteoarthritis by inhibiting NLRP3-mediated pyroptosis
por: Zu, Yan, et al.
Publicado: (2019)

Halotherapy relieves chronic obstructive pulmonary disease by alleviating NLRP3 inflammasome-mediated pyroptosis
por: Zhang, Chenyan, et al.
Publicado: (2022)

YTHDF1 alleviates sepsis by upregulating WWP1 to induce NLRP3 ubiquitination and inhibit caspase-1-dependent pyroptosis
por: Zhang, Shuyao, et al.
Publicado: (2022)

Paeonol regulates NLRP3 inflammasomes and pyroptosis to alleviate spinal cord injury of rat
por: Zhao, Houling, et al.
Publicado: (2022)

Ginsenoside Rg1 Inhibits Microglia Pyroptosis Induced by Lipopolysaccharide Through Regulating STAT3 Signaling
por: Yao, Yueyi, et al.
Publicado: (2021)

Curcumin Alleviates Aflatoxin B(1)-Induced Liver Pyroptosis and Fibrosis by Regulating the JAK2/NLRP3 Signaling Pathway in Ducks
por: Cui, Yilong, et al.
Publicado: (2023)

HSF1 Alleviates Brain Injury by Inhibiting NLRP3-Induced Pyroptosis in a Sepsis Model
por: He, Yi-fu, et al.
Publicado: (2023)

Schisandrin Inhibits NLRP1 Inflammasome-Mediated Neuronal Pyroptosis in Mouse Models of Alzheimer’s Disease
por: Li, Quan, et al.
Publicado: (2021)

LncRNA MALAT1 knockdown inhibits the development of choroidal neovascularization
por: Zhang, Xiaoli, et al.
Publicado: (2023)

Aerobic exercise alleviates pyroptosis-related diseases by regulating NLRP3 inflammasome
por: Hu, Shujuan, et al.
Publicado: (2022)

Ginsenoside compound K alleviates osteoarthritis by inhibiting NLRP3‑mediated pyroptosis
por: Li, Yuguo, et al.
Publicado: (2023)

Ginsenoside Rg1 Inhibits Microglia Pyroptosis Induced by Lipopolysaccharide Through Regulating STAT3 Signaling [Retraction]
Publicado: (2023)

Procyanidins alleviates morphine tolerance by inhibiting activation of NLRP3 inflammasome in microglia
por: Cai, Yang, et al.
Publicado: (2016)

Knockdown of the long non‑coding RNA MALAT1 ameliorates TNF‑α‑mediated endothelial cell pyroptosis via the miR‑30c‑5p/Cx43 axis
por: Yang, Zhang-Jian, et al.
Publicado: (2023)

Long Noncoding RNA MALAT1 and Colorectal Cancer: A Propensity Score Analysis of Two Prospective Cohorts
por: Li, Heng, et al.
Publicado: (2022)

TRIM45 aggravates microglia pyroptosis via Atg5/NLRP3 axis in septic encephalopathy
por: Huang, Xuliang, et al.
Publicado: (2023)

LRG1 promotes angiogenesis through upregulating the TGF-β1 pathway in ischemic rat brain
por: Meng, Hongmei, et al.
Publicado: (2016)

IP3R1 regulates Ca(2+) transport and pyroptosis through the NLRP3/Caspase-1 pathway in myocardial ischemia/reperfusion injury
por: Mo, Guixi, et al.
Publicado: (2021)

Fucoidan Alleviates Renal Fibrosis in Diabetic Kidney Disease via Inhibition of NLRP3 Inflammasome-Mediated Podocyte Pyroptosis
por: Wang, Mei-Zi, et al.
Publicado: (2022)

NLRP3-mediated pyroptosis in diabetic nephropathy
por: Wan, Jiayi, et al.
Publicado: (2022)

Pyroptosis in NLRP3 inflammasome-related atherosclerosis
por: Zeng, Xiang, et al.
Publicado: (2022)

Emodin Alleviates High-Glucose-Induced Pancreatic β-Cell Pyroptosis by Inhibiting NLRP3/GSDMD Signaling
por: Xing, Yiqian, et al.
Publicado: (2022)

Inhibited CSF1R Alleviates Ischemia Injury via Inhibition of Microglia M1 Polarization and NLRP3 Pathway
por: Du, Xiaoxue, et al.
Publicado: (2020)

Endoplasmic Reticulum Stress Mediated NLRP3 Inflammasome Activation and Pyroptosis in THP-1 Macrophages Infected with Bacillus Calmette-Guérin
por: Nie, Xueyi, et al.
Publicado: (2023)

The NLRP1 Inflammasome Induces Pyroptosis in Human Corneal Epithelial Cells
por: Griswold, Andrew R., et al.
Publicado: (2022)

IRE1α inhibition attenuates neuronal pyroptosis via miR-125/NLRP1 pathway in a neonatal hypoxic-ischemic encephalopathy rat model
por: Huang, Juan, et al.
Publicado: (2020)

GSK2656157, a PERK Inhibitor, Alleviates Pyroptosis of Macrophages Induced by Mycobacterium Bacillus Calmette–Guerin Infection
por: Ma, Boli, et al.
Publicado: (2023)

Dendrobium Nobile Lindl. Alkaloid Suppresses NLRP3-Mediated Pyroptosis to Alleviate LPS-Induced Neurotoxicity
por: Li, Dai-Di, et al.
Publicado: (2022)

PSMB5 Alleviates Ulcerative Colitis by Inhibiting ROS-Dependent NLRP3 Inflammasome-Mediated Pyroptosis
por: Han, Liang, et al.
Publicado: (2022)

Targeting NLRP3 Inflammasome Alleviates Synovitis by Reducing Pyroptosis in Rats with Experimental Temporomandibular Joint Osteoarthritis
por: Xin, Yinzi, et al.
Publicado: (2022)

NR4A1 suppresses pyroptosis by transcriptionally inhibiting NLRP3 and IL‐1β and co‐localizing with NLRP3 in trans‐Golgi to alleviate pathogenic bacteria‐induced colitis
por: Deng, Zhao, et al.
Publicado: (2021)

Knockdown of NEAT1 induces tolerogenic phenotype in dendritic cells by inhibiting activation of NLRP3 inflammasome
por: Zhang, Maomao, et al.
Publicado: (2019)

Knockdown of SEMA7A alleviates MPP(+)‐induced apoptosis and inflammation in BV2 microglia via PPAR‐γ activation and MAPK inactivation
por: Qi, Weinan, et al.
Publicado: (2023)

Long noncoding RNA MALAT1 knockdown reverses chemoresistance to temozolomide via promoting microRNA‐101 in glioblastoma
por: Cai, Tao, et al.
Publicado: (2018)

Reflections on the Role of Malat1 in Gynecological Cancer
por: Liao, Huiyan, et al.
Publicado: (2020)

The Molecular Mechanism of Long Non-Coding RNA MALAT1-Mediated Regulation of Chondrocyte Pyroptosis in Ankylosing Spondylitis
por: Chen, Wei, et al.
Publicado: (2022)

MALAT1 knockdown inhibits hypopharyngeal squamous cell carcinoma malignancy by targeting microRNA-194
por: Wang, Hongming, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_3d6r0ka46tc1arj9qb2fa4kqtn