TREM2 deficiency inhibits microglial activation and aggravates demyelinating injury in neuromyelitis optica spectrum disorder

Neuromyelitis optica spectrum disorder (NMOSD) is an inflammatory demyelinating disorder of the central nervous system (CNS) triggered by autoimmune mechanisms. Microglia are activated and play a pivotal role in response to tissue injury. Triggering receptor expressed on myeloid cells 2 (TREM2) is e...

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Detalles Bibliográficos
Autores principales: You, Yun-Fan, Chen, Man, Tang, Yue, Yu, Wen-Xiang, Pang, Xiao-Wei, Chu, Yun-Hui, Zhang, Hang, Shang, Ke, Deng, Gang, Zhou, Luo-Qi, Yang, Sheng, Wang, Wei, Xiao, Jun, Tian, Dai-Shi, Qin, Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10069075/
https://www.ncbi.nlm.nih.gov/pubmed/37013543
http://dx.doi.org/10.1186/s12974-023-02772-3

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