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The EffecTs of Amlodipine and other Blood PREssure Lowering Agents on Microvascular FuncTion in Small Vessel Diseases (TREAT-SVDs) trial: Study protocol for a randomised crossover trial

BACKGROUND: Hypertension is the leading modifiable risk factor for cerebral small vessel diseases (SVDs). Yet, it is unknown whether antihypertensive drug classes differentially affect microvascular function in SVDs. AIMS: To test whether amlodipine has a beneficial effect on microvascular function...

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Detalles Bibliográficos
Autores principales: Kopczak, Anna, Stringer, Michael S, van den Brink, Hilde, Kerkhofs, Danielle, Blair, Gordon W, van Dinther, Maud, Onkenhout, Laurien, Wartolowska, Karolina A, Thrippleton, Michael J, Duering, Marco, Staals, Julie, Middeke, Martin, André, Elisabeth, Norrving, Bo, Bousser, Marie-Germaine, Mansmann, Ulrich, Rothwell, Peter M, Doubal, Fergus N, van Oostenbrugge, Robert, Biessels, Geert Jan, Webb, Alastair JS, Wardlaw, Joanna M, Dichgans, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10069218/
https://www.ncbi.nlm.nih.gov/pubmed/37021189
http://dx.doi.org/10.1177/23969873221143570