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The EffecTs of Amlodipine and other Blood PREssure Lowering Agents on Microvascular FuncTion in Small Vessel Diseases (TREAT-SVDs) trial: Study protocol for a randomised crossover trial
BACKGROUND: Hypertension is the leading modifiable risk factor for cerebral small vessel diseases (SVDs). Yet, it is unknown whether antihypertensive drug classes differentially affect microvascular function in SVDs. AIMS: To test whether amlodipine has a beneficial effect on microvascular function...
Autores principales: | Kopczak, Anna, Stringer, Michael S, van den Brink, Hilde, Kerkhofs, Danielle, Blair, Gordon W, van Dinther, Maud, Onkenhout, Laurien, Wartolowska, Karolina A, Thrippleton, Michael J, Duering, Marco, Staals, Julie, Middeke, Martin, André, Elisabeth, Norrving, Bo, Bousser, Marie-Germaine, Mansmann, Ulrich, Rothwell, Peter M, Doubal, Fergus N, van Oostenbrugge, Robert, Biessels, Geert Jan, Webb, Alastair JS, Wardlaw, Joanna M, Dichgans, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10069218/ https://www.ncbi.nlm.nih.gov/pubmed/37021189 http://dx.doi.org/10.1177/23969873221143570 |
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