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Matrix-bound Cyr61/CCN1 is required to retain the properties of the bone marrow mesenchymal stem cell niche but is depleted with aging

Previously, we showed that extracellular matrices (ECMs), produced ex vivo by various types of stromal cells, direct bone marrow mesenchymal stem cells (BM-MSCs) in a tissue-specific manner and recapitulate physiologic changes characteristic of the aging microenvironment. In particular, BM-MSCs obta...

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Detalles Bibliográficos
Autores principales:	Marinkovic, Milos, Dai, Qiuxia, Gonzalez, Aaron O., Tran, Olivia N., Block, Travis J., Harris, Stephen E., Salmon, Adam B., Yeh, Chih-Ko, Dean, David D., Chen, Xiao-Dong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10069241/ https://www.ncbi.nlm.nih.gov/pubmed/35752272 http://dx.doi.org/10.1016/j.matbio.2022.06.004

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