Cargando…

PLK1 regulates CtIP and DNA2 interplay in long-range DNA end resection

DNA double-strand break (DSB) repair is initiated by DNA end resection. CtIP acts in short-range resection to stimulate MRE11–RAD50–NBS1 (MRN) to endonucleolytically cleave 5′-terminated DNA to bypass protein blocks. CtIP also promotes the DNA2 helicase–nuclease to accelerate long-range resection do...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ceppi, Ilaria, Cannavo, Elda, Bret, Hélène, Camarillo, Rosa, Vivalda, Francesca, Thakur, Roshan Singh, Romero-Franco, Amador, Sartori, Alessandro A., Huertas, Pablo, Guérois, Raphaël, Cejka, Petr
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2023
Materias:	Research Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10069449/ https://www.ncbi.nlm.nih.gov/pubmed/36746606 http://dx.doi.org/10.1101/gad.349981.122

Ejemplares similares

The internal region of CtIP negatively regulates DNA end resection
por: Howard, Sean Michael, et al.
Publicado: (2020)

Phosphorylated CtIP bridges DNA to promote annealing of broken ends
por: Öz, Robin, et al.
Publicado: (2020)

PLK1 targets CtIP to promote microhomology-mediated end joining
por: Wang, Hailong, et al.
Publicado: (2018)

CtIP-dependent DNA resection is required for DNA damage checkpoint maintenance but not initiation
por: Kousholt, Arne Nedergaard, et al.
Publicado: (2012)

ALC1/eIF4A1-mediated regulation of CtIP mRNA stability controls DNA end resection
por: Mejías-Navarro, Fernando, et al.
Publicado: (2020)

PLK1-mediated phosphorylation of PPIL2 regulates HR via CtIP
por: Qiu, Zhiyu, et al.
Publicado: (2022)

DNA end resection requires constitutive sumoylation of CtIP by CBX4
por: Soria-Bretones, Isabel, et al.
Publicado: (2017)

CtIP-mediated alternative mRNA splicing fine-tunes the DNA damage response
por: Prados-Carvajal, Rosario, et al.
Publicado: (2021)

The DNA resection protein CtIP promotes mammary tumorigenesis
por: Reczek, Colleen R., et al.
Publicado: (2016)

Human CtIP Mediates Cell Cycle Control of DNA End Resection and Double Strand Break Repair
por: Huertas, Pablo, et al.
Publicado: (2009)

CtIP is required for DNA damage-dependent induction of P21
por: Liu, Bo, et al.
Publicado: (2014)

CtIP tetramer assembly is required for DNA-end resection and repair
por: Davies, Owen R., et al.
Publicado: (2015)

DNA-dependent protein kinase promotes DNA end processing by MRN and CtIP
por: Deshpande, Rajashree A., et al.
Publicado: (2020)

Physiological protein blocks direct the Mre11–Rad50–Xrs2 and Sae2 nuclease complex to initiate DNA end resection
por: Reginato, Giordano, et al.
Publicado: (2017)

CtIP Mutations Cause Seckel and Jawad Syndromes
por: Qvist, Per, et al.
Publicado: (2011)

Neddylation inhibits CtIP-mediated resection and regulates DNA double strand break repair pathway choice
por: Jimeno, Sonia, et al.
Publicado: (2015)

BRCA1-CtIP interaction in the repair of DNA double-strand breaks
por: Aparicio, Tomas, et al.
Publicado: (2016)

CtIP is essential for telomere replication
por: Stroik, Susanna, et al.
Publicado: (2019)

Prognostic value of CtIP/RBBP8 expression in breast cancer
por: Soria-Bretones, Isabel, et al.
Publicado: (2013)

MRN, CtIP, and BRCA1 mediate repair of topoisomerase II–DNA adducts
por: Aparicio, Tomas, et al.
Publicado: (2016)

And-1 coordinates with CtIP for efficient homologous recombination and DNA damage checkpoint maintenance
por: Chen, Yali, et al.
Publicado: (2017)

SUMOylation mediates CtIP’s functions in DNA end resection and replication fork protection
por: Locke, Andrew J, et al.
Publicado: (2021)

The Role of Drosophila CtIP in Homology-Directed Repair of DNA Double-Strand Breaks
por: Yannuzzi, Ian, et al.
Publicado: (2021)

FANCJ helicase promotes DNA end resection by facilitating CtIP recruitment to DNA double-strand breaks
por: Nath, Sarmi, et al.
Publicado: (2020)

CtIP-dependent nascent RNA expression flanking DNA breaks guides the choice of DNA repair pathway
por: Gómez-Cabello, Daniel, et al.
Publicado: (2022)

ATM–Dependent MiR-335 Targets CtIP and Modulates the DNA Damage Response
por: Martin, Nathan T., et al.
Publicado: (2013)

WRN helicase and mismatch repair complexes independently and synergistically disrupt cruciform DNA structures
por: Mengoli, Valentina, et al.
Publicado: (2022)

Cullin3-KLHL15 ubiquitin ligase mediates CtIP protein turnover to fine-tune DNA-end resection
por: Ferretti, Lorenza P., et al.
Publicado: (2016)

The interaction between CtIP and BRCA1 is not essential for resection-mediated DNA repair or tumor suppression
por: Reczek, Colleen R., et al.
Publicado: (2013)

NBS1-CtIP–mediated DNA end resection suppresses cGAS binding to micronuclei
por: Abdisalaam, Salim, et al.
Publicado: (2022)

SIAH2 regulates DNA end resection and replication fork recovery by promoting CtIP ubiquitination
por: Jeong, Seo-Yeon, et al.
Publicado: (2022)

DNA end resection by Dna2-Sgs1-RPA and its stimulation by Top3-Rmi1 and Mre11-Rad50-Xrs2
por: Cejka, Petr, et al.
Publicado: (2010)

BRCA1 and CtIP Are Both Required to Recruit Dna2 at Double-Strand Breaks in Homologous Recombination
por: Hoa, Nguyen Ngoc, et al.
Publicado: (2015)

SERBP1 affects homologous recombination-mediated DNA repair by regulation of CtIP translation during S phase
por: Ahn, Jang-Won, et al.
Publicado: (2015)

USP52 regulates DNA end resection and chemosensitivity through removing inhibitory ubiquitination from CtIP
por: Gao, Ming, et al.
Publicado: (2020)

Structural basis for the coiled-coil architecture of human CtIP
por: Morton, C. R., et al.
Publicado: (2021)

CtIP-BRCA1 modulates the choice of DNA double-strand break repair pathway throughout the cell cycle
por: Yun, Maximina H., et al.
Publicado: (2009)

NF-κB regulates DNA double-strand break repair in conjunction with BRCA1–CtIP complexes
por: Volcic, Meta, et al.
Publicado: (2012)

Polo-like kinase 3 regulates CtIP during DNA double-strand break repair in G1
por: Barton, Olivia, et al.
Publicado: (2014)

CSB interacts with BRCA1 in late S/G2 to promote MRN- and CtIP-mediated DNA end resection
por: Batenburg, Nicole L, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_t956umgpgtcv0d4c41a2v6nlk1