Atlas-scale single-cell chromatin accessibility using nanowell-based combinatorial indexing

Here we present advancements in single-cell combinatorial indexed Assay for Transposase Accessible Chromatin (sciATAC) to measure chromatin accessibility that leverage nanowell chips to achieve atlas-scale cell throughput (>10(5) cells) at low cost. The platform leverages the core of the sciATAC...

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Detalles Bibliográficos
Autores principales: O'Connell, Brendan L., Nichols, Ruth V., Pokholok, Dmitry, Thomas, Jerushah, Acharya, Sonia N., Nishida, Andrew, Thornton, Casey A., Co, Marissa, Fields, Andrew J., Steemers, Frank J., Adey, Andrew C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2023
Materias:
Methods
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10069466/
https://www.ncbi.nlm.nih.gov/pubmed/36792372
http://dx.doi.org/10.1101/gr.276655.122

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