Nose to Brain Delivery of Astaxanthin–Loaded Nanostructured Lipid Carriers in Rat Model of Alzheimer’s Disease: Preparation, in vitro and in vivo Evaluation

BACKGROUND: Astaxanthin (AST) is a second-generation antioxidant with anti-inflammatory and neuroprotective properties and could be a promising candidate for Alzheimer’s disease (AD) therapy, but is shows poor oral bioavailability due to its high lipophilicity. PURPOSE: This study aimed to prepare a...

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Detalles Bibliográficos
Autores principales: Shehata, Mustafa K, Ismail, Assem A, Kamel, Maher A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10069509/
https://www.ncbi.nlm.nih.gov/pubmed/37020692
http://dx.doi.org/10.2147/IJN.S402447

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10069509/
https://www.ncbi.nlm.nih.gov/pubmed/37020692
http://dx.doi.org/10.2147/IJN.S402447

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