Cargando…
Relationship between lysine methyltransferase levels and heterochromatin gene repression in living cells and in silico
Gene regulation plays essential roles in all multicellular organisms, allowing for different specialized tissue types to be generated from a complex genome. Heterochromatin-driven gene repression, associated with a physical compaction of the genome, is a pathway involving core components that are co...
Autores principales: | Yan, Xiaokang, Williams, Michael R, Barboza Castillo, Ameriks D, Kireev, Dmitri, Hathaway, Nathaniel A |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10069619/ https://www.ncbi.nlm.nih.gov/pubmed/37020498 http://dx.doi.org/10.1093/pnasnexus/pgad062 |
Ejemplares similares
-
A simulation model of heterochromatin formation at submolecular detail
por: Williams, Michael R., et al.
Publicado: (2022) -
The preRC protein ORCA organizes heterochromatin by assembling histone H3 lysine 9 methyltransferases on chromatin
por: Giri, Sumanprava, et al.
Publicado: (2015) -
Contribution of promoter DNA sequence to heterochromatin formation velocity and memory of gene repression in mouse embryo fibroblasts
por: Vignaux, Patricia A., et al.
Publicado: (2019) -
Histone H3 lysine 4 methyltransferase is required for facultative heterochromatin at specific loci
por: Zhu, Qiaoqiao, et al.
Publicado: (2019) -
Evolution-inspired engineering of anthracycline methyltransferases
por: Dinis, Pedro, et al.
Publicado: (2023)