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Development of the Commercial Manufacturing Process for Nirmatrelvir in 17 Months
[Image: see text] The advancement of nirmatrelvir, the active ingredient in Paxlovid, from discovery to emergency use authorization was achieved in just 17 months, requiring an unprecedented rate of chemical process development.
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10069651/ https://www.ncbi.nlm.nih.gov/pubmed/37252346 http://dx.doi.org/10.1021/acscentsci.3c00145 |
| _version_ | 1785018889816506368 |
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| author | Allais, Christophe Connor, Christina G. Do, Nga M. Kulkarni, Samir Lee, Johnny W. Lee, Taegyo McInturff, Emma Piper, Jared Place, Dave W. Ragan, John A. Weekly, R. Matt |
| author_facet | Allais, Christophe Connor, Christina G. Do, Nga M. Kulkarni, Samir Lee, Johnny W. Lee, Taegyo McInturff, Emma Piper, Jared Place, Dave W. Ragan, John A. Weekly, R. Matt |
| author_sort | Allais, Christophe |
| collection | PubMed |
| description | [Image: see text] The advancement of nirmatrelvir, the active ingredient in Paxlovid, from discovery to emergency use authorization was achieved in just 17 months, requiring an unprecedented rate of chemical process development. |
| format | Online Article Text |
| id | pubmed-10069651 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2023 |
| publisher | American Chemical Society |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-100696512023-04-04 Development of the Commercial Manufacturing Process for Nirmatrelvir in 17 Months Allais, Christophe Connor, Christina G. Do, Nga M. Kulkarni, Samir Lee, Johnny W. Lee, Taegyo McInturff, Emma Piper, Jared Place, Dave W. Ragan, John A. Weekly, R. Matt ACS Cent Sci [Image: see text] The advancement of nirmatrelvir, the active ingredient in Paxlovid, from discovery to emergency use authorization was achieved in just 17 months, requiring an unprecedented rate of chemical process development. American Chemical Society 2023-03-29 /pmc/articles/PMC10069651/ /pubmed/37252346 http://dx.doi.org/10.1021/acscentsci.3c00145 Text en Published 2023 by American Chemical Society https://creativecommons.org/licenses/by/4.0/Permits the broadest form of re-use including for commercial purposes, provided that author attribution and integrity are maintained (https://creativecommons.org/licenses/by/4.0/). |
| spellingShingle | Allais, Christophe Connor, Christina G. Do, Nga M. Kulkarni, Samir Lee, Johnny W. Lee, Taegyo McInturff, Emma Piper, Jared Place, Dave W. Ragan, John A. Weekly, R. Matt Development of the Commercial Manufacturing Process for Nirmatrelvir in 17 Months |
| title | Development of
the Commercial Manufacturing Process
for Nirmatrelvir in 17 Months |
| title_full | Development of
the Commercial Manufacturing Process
for Nirmatrelvir in 17 Months |
| title_fullStr | Development of
the Commercial Manufacturing Process
for Nirmatrelvir in 17 Months |
| title_full_unstemmed | Development of
the Commercial Manufacturing Process
for Nirmatrelvir in 17 Months |
| title_short | Development of
the Commercial Manufacturing Process
for Nirmatrelvir in 17 Months |
| title_sort | development of
the commercial manufacturing process
for nirmatrelvir in 17 months |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10069651/ https://www.ncbi.nlm.nih.gov/pubmed/37252346 http://dx.doi.org/10.1021/acscentsci.3c00145 |
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