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Development of the Commercial Manufacturing Process for Nirmatrelvir in 17 Months
[Image: see text] The advancement of nirmatrelvir, the active ingredient in Paxlovid, from discovery to emergency use authorization was achieved in just 17 months, requiring an unprecedented rate of chemical process development.
Autores principales: | Allais, Christophe, Connor, Christina G., Do, Nga M., Kulkarni, Samir, Lee, Johnny W., Lee, Taegyo, McInturff, Emma, Piper, Jared, Place, Dave W., Ragan, John A., Weekly, R. Matt |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10069651/ https://www.ncbi.nlm.nih.gov/pubmed/37252346 http://dx.doi.org/10.1021/acscentsci.3c00145 |
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